Inert tracer gas washout from mixed venous blood: the sloping alveolar plateau
نویسندگان
چکیده
منابع مشابه
Intrapulmonary gas mixing and the sloping alveolar plateau in COPD patients with macroscopic emphysema.
Chronic obstructive pulmonary disease patients, especially those with emphysema, show steep slopes of the alveolar plateau (S). This study tested the hypothesis that continued gas exchange between poorly and well-ventilated lung units by means of collateral ventilation would contribute to S in these patients. Nine young volunteers, nine older volunteers and 11 patients with macroscopic emphysem...
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AFFILIATIONS: 1. Queens Silvia Children’s Hospital, Göteborg, and Department of Pediatrics, The Sahlgrenska Academy at Göteborg, Sweden. 2. Erasmus Medical CenterSophia Children’s Hospital, Department of Pediatric Pulmonology and Allergology, Rotterdam, the Netherlands. 3. Meander Medical Center, Department of Radiology, Amersfoort, the Netherlands. 4. University Medical Center Utrecht, Departm...
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We describe a method to determine the phase III slope for the purpose of calculating indexes of ventilation heterogeneity, S(acin) and S(cond), from the multiple breath nitrogen washout test (MBNW). Our automated method applies a recursive, segmented linear regression technique to each breath of the MBNW test and determines the best point of transition, or breakpoint, between each phase of the ...
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Ventilation inhomogeneity, measured using multiple breath washout (MBW), reflects small airway function and has emerged as a valuable tool in cystic fibrosis (CF). Improved sensitivity to detect early lung damage has been suggested from preschool children through to adults and confirmed in high-resolution CT (HRCT) studies. Longitudinal utility is now emerging. A large number of parameters refl...
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I nert gas washout tests including single breath washout (SBW) and multiple breath washout (MBW) have been used for several decades across a wide age range spanning from early infancy to late adulthood. In the past, these lung function tests were typically applied in research settings, assessing lung volume and ventilation distribution in order to gain insight into presence, severity and progre...
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ژورنال
عنوان ژورنال: Respiration Physiology
سال: 1982
ISSN: 0034-5687
DOI: 10.1016/0034-5687(82)90024-x